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Led by Mala Shanmugam, we study the role of Metabolism in Myeloma.
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Mala Shanmugam, PhD, MS, is an Assistant Professor in the Department of Hematology and Medical Oncology at Emory University, School of Medicine. Dr. Shanmugam is a member of the Cancer Cell Biology Research Program and the Molecular and Systems Pharmacology at GDBBS Emory. Dr. Shanmugam attended Madurai Kamaraj University in T. Nadu, India where she earned a MS in Biotechnology. She received her PhD in Tumor Cell Biology from Northwestern University Medical School in Chicago, IL. She completed her fellowship training at Northwestern University Medical School and at Loyola University of Chicago Medical Center. |
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Education: Institute of Microbial Technology, Jawaharlal Nehru University (PhD, Molecular Biology) CSJM University (MS, Biotechnology) Lucknow University (BS, Botany/Chemistry) Research Focus: Multiple Myeloma, Apoptosis, BCL-2 proteins, Metabolism Email: richa.bajpai@emory.edu |
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Education: Georgia Tech (MS+PhD, Bioengineering) IIT Delhi (BS+MT, Biochemical Engineering and Biotechnology) Research Focus: Lung Adenocarcinoma, Collective Cell Invasion, Metabolism Email: aditi.sharma@emory.edu |
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Education: Georgia Tech (BS, Biomedical Engineering) Research Focus: Multiple Myeloma, Apoptosis, BCL-2 proteins, Metabolism Email: arusha.ayesha.siddiqa@emory.edu |
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Education: Emory (Rising junior, Chemistry and Biology) Email: kim.amelsberg@emory.edu |
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Education: Choate High School (Rising senior) Email: ewedge19@choate.edu |
Evaluating the Efficacy of GLUT Inhibitors Using a Seahorse Extracellular Flux Analyzer.
Wei C, Heitmeier M, Hruz PW, Shanmugam M.
Methods in Molecular Biology, 2018
Development of GLUT4-selective antagonists for multiple myeloma therapy
Changyong Wei, Richa Bajpai, Horrick Sharma, Monique Heitmeier, Atul D. Jain, Shannon M. Matulis, Ajay K. Nooka,
Rama K. Mishra, Paul W. Hruz, Gary E. Schiltz, Mala Shanmugam
European Journal of Medicinal Chemistry, 2017
Targeting glutamine metabolism in multiple myeloma enhances BIM binding to BCL-2 eliciting synthetic lethality to ABT-199
Richa Bajpai, Shannon M Matulis, Changyong Wei, Ajay K Nooka, Hayley E Von Holen, Sagar Lonial, Lawrence H Boise
and Mala Shanmugam
Oncogene, 2016
In Silico Modeling-based Identification of GLUT4 Selective Inhibitors for Cancer Therapy